{"id":223500,"date":"2020-11-18T15:09:42","date_gmt":"2020-11-18T23:09:42","guid":{"rendered":"https:\/\/siliconeer.com\/current\/?p=223500"},"modified":"2020-11-23T14:25:08","modified_gmt":"2020-11-23T22:25:08","slug":"will-communities-hardest-hit-get-covid-19-vaccines","status":"publish","type":"post","link":"https:\/\/siliconeer.com\/current\/will-communities-hardest-hit-get-covid-19-vaccines\/","title":{"rendered":"Will Communities Hardest Hit Get Covid 19 Vaccines?"},"content":{"rendered":"

(Above):<\/strong>\u00a0(Inset,\u00a0Clockwise from top left): Dr. Ashish K. Jha, Dean, Brown University School of Public Health; Dr. William Schaffner, Professor of Preventive Medicine, Department of Health Policy and Professor of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine; Dr. Tung Nguyen, Stephen J. McPhee, MD Endowed Chair in General Internal Medicine, Professor of Medicine, University of California, San Francisco; and Dr. Nirav R. Shah, Senior Scholar, Stanford University Clinical Excellence Research Center. (Siliconeer\/EMS\/iStock)<\/em><\/p>\n

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By Sunita Sohrabji\/EMS Contributing Editor<\/em><\/strong><\/p>\n

The U.S. is weeks away from rolling out COVID vaccines, but pandemic experts say the challenges of vaccinating people will be acute, especially in communities of color.<\/p>\n

\u201cVaccines don\u2019t save lives: vaccinations do,\u201d said Dr. Ashish Jha, Dean of the Brown University School of Public Health, speaking at a Nov. 13 briefing organized by Ethnic Media Services and moderated by Dr. Tung Nguyen, professor of medicine at the University of California, San Francisco.<\/p>\n

\u201cThere’s a huge challenge from a supply chain perspective to getting the vaccines out,\u201d said Jha, noting that the vaccines will have to be stored and delivered frozen. More challenging is \u201cvaccine hesitancy,\u201d especially in communities of color who have been hit hardest by the pandemic, he said.<\/p>\n

Jha predicted 100,000 more deaths from COVID in the U.S. before the new Biden-Harris administration is inaugurated on Jan. 20, 2021. \u201cWe are in the worst moment of the pandemic right now.\u201d<\/p>\n

Dr. Nirav Shah, adjunct professor of medicine in the Division of Primary Care and Population Health at Stanford University stated: \u201cWe need to do this in a more structured and standardized way as opposed to the thousand points of light approach where every state, every city is doing something on their own. Simple coordination, using evidence-based approaches, will make a big difference here.\u201d<\/p>\n

Dr. William Schaffner, professor of Medicine, Division of Infectious Diseases at Vanderbilt University, agreed that vaccine delivery would pose enormous challenges. \u201cThis is not a vaccine that will be available at the local pharmacy or in a physician’s office,\u201d he said.<\/p>\n

Schaffner also noted that the vaccine is reactive: people taking it may experience a sore arm, fever, or headaches. Nguyen warned that such side effects could increase people\u2019s distrust of the vaccine, and deter them from getting the shot.<\/p>\n

Skepticism of the vaccine is strong in the African American community and other ethnic communities, said Schaffner. \u201cSo we’re going to have to do everything we can to reach out and provide information and also provide reassurance,\u201d he said, noting that much of the work will have to be done through churches or by prominent leaders in ethnic communities.<\/p>\n

Pfizer and Germany-based BioNTech announced Nov. 9 that they had jointly developed a vaccine with an efficacy rate of 90 percent. The study enrolled 43,538 participants, with 42 percent coming from diverse backgrounds. The companies have submitted an application for emergency use authorization to the Food and Drug Administration. The application is expected to be approved by the end of November.<\/p>\n

Concurrently, Moderna announced the results of its trial Nov. 16 which had an efficacy rate of 94 percent. Approximately 37 percent of the participants in the Moderna trial were people of color.<\/p>\n

Jha noted that a 90 percent efficacy rate for the Pfizer vaccine was astounding. \u201cI was speaking at a conference and saying that we will be lucky if the vaccine is 60 to 70 percent effective. A 90 percent efficacy was not what I was expecting and am I happy to be wrong on that,\u201d he said.<\/p>\n

\u201cWe’re not just testing it in 18 to 30 year old white men and women, but in fact we’re testing it in a broad swath of America,\u201d said Jha, noting that the Moderna trial was delayed as the company tried to diversify its testing recruits.<\/p>\n

Shah said the news from Pfizer, which indicated efficacy of the vaccine with just two doses, was an enormous step in the right direction. But once the vaccine is approved with by the FDA with emergency use authorization, it is unlikely that most people will be able to get vaccinated right away. A maximum of 10 to 20 million doses will be available by the end of the year, he said.<\/p>\n

\u201cThere will be a ramp up after that, but it is going to be some time before we get the kind of widespread availability of multiple vaccines with secure supply chains that get everyone the two doses,\u201d said Shah.<\/p>\n

Schaffner said treatment for people infected with COVID is getting better. \u201cWe’re doing a better job of getting people out of the Intensive Care Unit and out of the hospital; we are lowering the fatality rate.\u201d<\/p>\n

He also spoke about the use of the antiviral medication Remdesivir, which was approved last month by the FDA, and\u00a0 dexamethasone, a steroid that helps control the inflammatory response during the second half of the infection.<\/p>\n

Monoclonal antibodies also received emergency use authorization Nov. 9, but Schaffner said the intravenous treatment poses a challenge as to who should get those and at what stage of the infection.<\/p>\n

All four physicians agreed that a coordinated effort by the incoming administration \u2014 as opposed to the current patchwork quilt of efforts \u2014 would help the U.S. get the pandemic under control. Jha said he was astounded that some states have closed their schools but opened their casinos.<\/p>\n

He noted that the President-elect has no formal powers yet, but can use his soft powers to go out to red states and let people know why wearing a mask is effective.<\/p>\n

Nguyen said the Biden Administration must impose a national mandatory mask mandate. \u201cIf we all had worn masks in the last seven months, we would have 100,000 less deaths,\u201d he stated.<\/p>\n

\u201cWe do not have a silver bullet,\u201d said Shah. \u201cTesting alone won\u2019t work. Contact tracing alone won\u2019t work. Physical distancing alone won’t work. Wearing masks alone won’t work.\u201d<\/p>\n

\u201cBut all of these together will collectively bring us to where we need to be, so that we actually see cases go down,\u201d he said.<\/p>\n

Videos from the briefing:<\/strong><\/p>\n